Predictors of response to cognitive-behavioral therapy in patients with posttraumatic stress disorder: a systematic review / Preditores de resposta à terapia cognitivo-comportamental em pacientes com transtorno de estresse pós-traumático: uma revisão sistemática

OBJETIVO: O transtorno de estresse pós-traumático (TEPT) é um transtorno altamente prevalente e incapacitante. Mesmo quando tratado com uma intervenção de primeira linha, terapia cognitivo-comportamental (TCC), 45% dos pacientes continuam sofrendo desse transtorno. Portanto, conhecer os fatores que podem prever quem responderá à TCC seria de grande valor no tratamento desses pacientes. Por esse motivo, revisamos sistematicamente a literatura para identificar as variáveis que poderiam predizer a resposta à TCC em pacientes que sofrem de TEPT. MÉTODOS: Seguindo as diretrizes do PRISMA 2020, pesquisamos em banco de dados eletrônico como ISI Web of Science, Scopus, PsycINFO, MEDLINE e PTSDpubs até novembro de 2021. Dois autores conduziram independentemente a seleção do estudo e a extração de dados. Estudos que examinaram possíveis preditores de resposta à terapia, com amostra de adultos (18-65 anos) de ambos os sexos, com e sem comorbidades, foram considerados elegíveis. As características dos estudos foram sintetizadas em uma tabela. O risco de viés foi avaliado pela ferramenta de avaliação de qualidade de risco de viés da Cochrane. RESULTADOS: Vinte e oito estudos envolvendo 15 variáveis foram selecionados. Desses, oito mostraram baixo risco de viés, 19 mostraram algumas preocupações e um mostrou alto risco potencial de viés. A relação terapêutica foi a única variável considerada um preditor de boa resposta à terapia. Todas as outras variáveis apresentaram resultados conflitantes. CONCLUSÕES: A variável mais promissora, embora muito fraca cientificamente, é a relação terapêutica. Ensaios clínicos randomizados adicionais devem ser conduzidos para esclarecer o papel dessa variável como um preditor de resposta da TCC em pacientes com TEPT.

OBJECTIVE: Posttraumatic stress disorder (PTSD) is a highly prevalent and disabling disorder. Even when treated with the first-line intervention, cognitive-behavioral therapy (CBT), 45% of the patients continue suffering from this disorder. Therefore, knowing the factors that could foresee who will respond to CBT would be of great value to the treatment of these patients. Thus, we have systematically reviewed the literature to identify the variables that could predict response to CBT in patients suffering from PTSD. METHODS: Following the PRISMA 2020 guidelines, we searched the electronic databases ISI Web of Science, Scopus, PsycINFO, MEDLINE, and PTSDpubs until November 2021. Two authors have independently conducted study selection and data extraction. Studies that examined possible predictors of response to therapy on a sample of adults (18-65 years), both genders, with and without comorbidities were considered eligible. The characteristics of the studies were synthesized in a table. The risk of bias was assessed by the Cochrane risk of bias quality assessment tool. RESULTS: Twenty- -eight studies comprising 15 variables were selected. Among those, eight showed a low risk of bias, 19 showed some concerns, and one showed a high potential risk of bias. The therapeutic relationship was the only variable considered to be a predictor of a good response to therapy. All other variables showed conflicting results. CONCLUSIONS: The most promising variable, although scientifically weak, is the therapeutic relationship. Additional randomized clinical trials should be conducted to clarify the role of this variable as a predictor of response to CBT in patients with PTSD.

Terapia Cognitivo Conductual en pacientes con trauma infantil diverso: Evidencia de reducción de síntomas. Artículo de Revisión / Cognitive Behavioral Therapy in patients with diverse childhood trauma: Evidence of symptom reduction. Review article

La presentación de un evento traumático único o sistemático en la infancia, puede afectar el curso normal del desarrollo psíquico del infante en sus etapas evolutivas si no es abordado oportuna y adecuadamente. Métodos: Se realizó una búsqueda de artículos, de los últimos 5 años, que abordasen el efecto de la Terapia Cognitivo Conductual Centrada en el Trauma (TCC-CT) en niños y adolescentes. Resultados: Las experiencias de trauma en la primera infancia son un problema real y no infrecuentes, con efecto sobre varios dominios del desarrollo y salud del infante, por ello, es de gran importancia un tratamiento oportuno basado en la evidencia. Esta terapia es un tratamiento efectivo y ampliamente utilizado para abordar el trauma infantil. Discusión: Los artículos revisados, respaldan la TCCCT como un tratamiento efectivo y ampliamente utilizado para abordar el trauma infantil, con vasta evidencia.

The presentation of a single or systematic traumatic event in childhood can affect the normal course of the infant's psychic development in its evolutionary stages if it is not approached in a timely and adequate manner. Methods. A search was carried out for articles, from the last 5 years, that addressed the effect of Trauma-Focused Cognitive Behavioral Therapy (CBT-CT) in children and adolescents. Results. The experiences of trauma in early childhood are a real problem and not infrequent, with an effect on several domains of development and health of the infant, therefore, the great importance of a timely treatment based on evidence. This therapy is an effective and widely used treatment to address childhood trauma. Discussion. The revised articles support CBT-CT as an effective and used treatment to address childhood trauma, with ample evidence.

Advances in Treatment of Post-Traumatic Stress Disorder with Chinese Medicine / 中国结合医学杂志

"Timely, near, and expectation" is the main principle of battlefield rescue for military combat stress reaction (CSR). Post-traumatic stress disorder (PTSD) is the most common form of CSR and a long-term persistent mental disorder that is caused by unusual threatening or catastrophic psychological trauma. Chinese medicine (CM) has abundant resources, is simple, easy to master, with few side effects. This article summarizes the cellular and animal experimental mechanisms of CM treatment on PTSD, suggesting that traditional Chinese herbs and acupuncture can protect brain functional areas, and adjust hypothalamus-pituitary-adrenal axis. Traditional Chinese herbs and acupuncture have shown good anti-stress efficacy and fewer side effects in clinical application, which may improve the CSR in the battlefield.

Efficacy, patient-doctor relationship, costs and benefits of utilizing telepsychiatry for the management of post-traumatic stress disorder (PTSD): a systematic review

Abstract Introduction Post-traumatic stress disorder (PTSD) is one of the most common psychiatric disorders found among victims of disaster, kidnapping, accidents, sexual assaults and war in Indonesia. However, lacking and unequal distribution of psychiatric medical personnel remains a barrier to its management. This review aims to introduce and evaluate the potential contribution of telepsychiatry to the management of PTSD based on published literature. Methods Original studies were obtained from PubMed, Science Direct, ProQuest, High Wire, and Elsevier Clinical Key databases. Results A total of 125 articles were found, of which 15 articles (12 randomized controlled trials, 2 open trials and 1 pilot study) fulfilled the inclusion criteria. A total of 991 subjects were found with a follow-up period ranging between 5 weeks and 18 months. Telepsychiatry is an innovative use of technology to aid the delivery of PTSD treatments in areas difficult to reach. The quality of care given by telepsychiatry both through video conferencing as well as web- and application-based is comparable to that of face-to-face therapy. Patient satisfaction, quality of doctor-patient relationship also remains high, with lower costs and shorter therapeutic time when compared to face-to-face therapy. Conclusion Various studies have shown that telepsychiatry is an effective solution for the management of PTSD. Studies have also reported that the quality of treatment through telepsychiatry is as effective as face-to-face therapy, with greater efficiency. Countries, especially those with a low patient-to-mental health professional ratio, should be encouraged to develop telepsychiatry systems to manage PTSD.

Terapia de Exposição Narrativa (NET): estudo de avaliabilidade em dois serviços de saúde no município do Rio de Janeiro / Narrative Exposure Therapy (NET): evaluability study in two health services in the city of Rio de Janeiro

Esta dissertação tem como objeto o estudo de avaliabilidade do projeto piloto da "NET para sobreviventes de violência: uma proposta piloto de implementar atendimento terapêutico nos serviços de atenção básica para pacientes com sintomas de TEPT". que oferece cuidados à saúde de indivíduos expostos à violência e com Transtorno de Estresse Pós Traumático, desenvolvido em dois serviços públicos de saúde do município do Rio de Janeiro. A exposição a eventos traumáticos, como violências e acidentes podem provocar sintomas como: pensamentos intrusivos, pesadelos, hipervigilância, flashback, anestesia emocional e afastamento de atividades sociais, que fazem parte do TEPT e que que correspondem a altos custos tanto a população envolvida, quanto para os serviços de assistência a saúde e segurança. Tratamentos para o TEPT têm a psicoterapia focada no trauma como uma das mais eficientes. A terapia de exposição narrativa foi desenvolvida especificamente para o tratamento de TEPT e sobreviventes de violência organizada e múltiplos traumas. O estudo incluiu as etapas de mapeamento da intervenção, identificação de stakeholders, construção de um modelo lógico e da análise estratégica. Para isso utilizou-se a metodologia de análise documental, entrevistas semiestruturadas e análise de conteúdo, que permitiram mapear o histórico e documentos sobre a intervenção NET e analisar as ações desenvolvidas, identificando as barreiras e potencialidades, assim como as lacunas em relação aos princípios estabelecidos pelo SUS e pela Reforma psiquiátrica com os investimentos nos serviços de saúde no Rio de Janeiro. Foi possível identificar que um dos maiores obstáculos da implementação foi a própria instabilidade do contexto político, estrutura física e recursos humanos a que estão sujeitos os serviços públicos de saúde. Sobre as potencialidades, concluímos, que o projeto NET é avaliável, sendo profícuo dar continuidade ao processo de avaliação, levando em consideração que o projeto piloto NET alcançou seus objetos iniciais como a capacitação de profissionais da saúde no atendimento terapêutico de qualidade, breve e baseado em evidências voltado para vítimas de violência que desenvolveram o Transtorno do Estresse Pós-Traumático.

This dissertation has the object the evaluability assessment of a pilot project of "NET for survivors of violence: a pilot proposal for implementing therapeutic care in primary care services for patients with PTSD symptoms". which offers health care to individuals exposed to violence and post-traumatic stress disorder, developed in two public health services in the city of Rio de Janeiro. Exposure to traumatic events, such as violations and accidents, can cause symptoms such as: intrusive thoughts, nightmares, hypervigilance, flashback, emotional anesthesia and withdrawal from social activities, which are part of PTSD and which have high costs both in the participation involved, and for health and safety assistance services. Treatments for PTSD have trauma-focused psychotherapy as one of the most effective. The Therapeutic Exposure Narrative was developed specifically for the treatment of PTSD and survivors of organized violence and multiple traumas. The study included the steps of mapping the intervention, identifying stakeholders, building a logical model and strategic analysis. For that, the document analysis methodology, semi-structured interviews and content analysis were used, which allowed to map the history and documents about the NET intervention and to analyze the actions developed, identifying the barriers and potentialities, as well as the gaps in relation to the established principles. by SUS and the Psychiatric Reform with investments in health services in Rio de Janeiro. It was possible to identify that one of the biggest obstacles to implementation was the instability of the political context, physical structure and human resources to which public health services are subject. Regarding the potentialities, we conclude that the NET project is evaluable, and it is useful to continue the evaluation process, taking into account that the NET pilot project reached its initial objectives, such as the training of health professionals in quality therapeutic assistance, brief and based evidence aimed at victims of violence who developed Posttraumatic Stress Disorder.

Does CBT have lasting effects in the treatment of PTSD after one year of follow-up? A systematic review of randomized controlled trials / A TCC possui efeitos duradouros no tratamento do TEPT após um ano de seguimento? Revisão sistemática de ensaios clínicos randomizados

Abstract Introduction: While several previous meta-analyses have documented the short-term efficacy of cognitive-behavioral therapy (CBT), its long-term efficacy remains unknown. Posttraumatic stress disorder (PTSD) is a serious, debilitating, often chronic and disabling disease. Objective: To estimate the long-term efficacy of CBT in the treatment of PTSD by assessing the maintenance of the effect after one year of follow-up. Method: We performed a systematic review through electronic database searches including ISI Web of Science, PubMed, PsycInfo and Pilots. We included randomized studies in which CBT was compared with a control group (waiting list or usual care) in adults with PTSD that reported at least one year of CBT follow-up. Results: Our search identified 2,324 studies and 8 were selected. CBT was shown to be effective in the treatment of PTSD in the post-treatment period. Improvement in PTSD symptoms was statistically significant in relation to the control group. The improvement observed in the treatment group or single group (formed by both treatment group and control group, which was submitted to the intervention after a few weeks on the waiting list) was maintained in the follow-up. Conclusion: Due to the lack of control groups in the follow-up period in six of the eight studies included in this review, there is still no proper methodological basis to assert that CBT has lasting effects in the treatment of PTSD. Our study found serious methodological shortcomings and the need to fill this gap in the literature through the development of studies with robust and sophisticated designs.

Resumo Introdução: Várias meta-análises anteriores documentaram a eficácia a curto prazo da terapia cognitivo-comportamental (TCC). No entanto, sua eficácia a longo prazo permanece desconhecida. O transtorno de estresse pós-traumático (TEPT) é uma doença crônica grave, debilitante e incapacitante. Objetivo: Estimar a eficácia a longo prazo da TCC no tratamento do TEPT, avaliando a manutenção do efeito após um ano de seguimento. Métodos: Realizamos uma revisão sistemática através de pesquisas nas bases de dados eletrônicas ISI Web of Science, PubMed, PsycInfo e Pilots. Incluímos estudos randomizados nos quais a TCC foi comparada com um grupo controle (lista de espera ou tratamento usual) em adultos com TEPT que relataram pelo menos um ano de seguimento da TCC. Resultados: A pesquisa identificou 2.324 estudos e 8 foram selecionados. A TCC mostrou-se eficaz no tratamento do TEPT no período pós-tratamento. A melhora nos sintomas de TEPT foi estatisticamente significativa em relação ao grupo controle. A melhora observada no grupo de tratamento ou grupo único (formado por ambos os grupos de tratamento e controle, que foi submetido à intervenção após algumas semanas na lista de espera) foi mantida no seguimento. Conclusão: Devido à ausência de grupo controle no período de follow-up em 6 dos 8 estudos incluídos nesta revisão, ainda não há base metodológica adequada para afirmar que a TCC tem efeitos duradouros no tratamento do TEPT. Nosso estudo encontrou graves deficiências metodológicas e a necessidade de preencher essa lacuna na literatura através de estudos com delineamentos robustos e sofisticados.

Reactividad del cortisol y salud mental en adultos expuestos a violencia temprana: revisión sistemática / Cortisol reactivity and adult mental health in adults exposed to early violence: a systematic review / Reatividade do cortisol e saúde mental em adultos com exposição precoce à violência: uma revisão sistemática

RESUMEN Objetivo Analizar los resultados con respecto a la reactividad del cortisol (RC) ante un paradigma de estrés experimental en adultos con o sin algún trastorno psiquiátrico que sufrieron violencia en etapas tempranas de desarrollo (infancia y adolescencia temprana) y con ello proponer una herramienta clínica para el establecimiento de indicadores biológicos de estrés. Métodos Se realizó una revisión sistemática en diversas bases de datos, siguiendo los criterios PRISMA; de un total de 231 artículos, 16 cumplieron los criterios de inclusión y los resultados fueron analizados de manera cualitativa. Resultados A pesar de la heterogeneidad, los resultados sugieren que las personas que sufrieron violencia temprana presentan un patrón de baja RC. Contrariamente, la población que además desarrolló síntomas de trastorno de estrés postraumático y depresión, independientemente del tipo de violencia, mostró incrementada RC. La mayoría de los trabajos se centraron en población que sufrió abuso sexual en la infancia y la mitad de los artículos apoya la hipótesis de que la RC es más pronunciada en hombres que en mujeres. Conclusiones Los resultados de esta revisión nos permiten sugerir que es posible considerar la hiperreactividad del cortisol como un biomarcador para el tratamiento e intervención de población con trastorno de estrés postraumático y depresión que sufrieron violencia temprana. Además, apoyan la evidencia de que sufrir violencia altera la respuesta del estrés y la salud mental a largo plazo. Sin embargo, es necesario realizar más estudios principalmente los que se refieren a la hiporreactividad y a las diferencias de género.

ABSTRACT Objective Analyze results with respect to cortisol reactivity (CR) in experimental stress paradigms in adults with or without a psychiatric disorder who suffered violence in early developmental stages (infancy or early adolescence); and use these results to propose a clinical tool to determine biological stress indicators. Methods A systematic review was conducted using several databases and following PRISMA criteria; of a total of 231 articles, 16 satisfied the inclusion criteria and the results were analyzed qualitatively. Results Despite heterogeneity, the results suggested that the people who suffered violence at an early age present a pattern of low CR. In contrast, people who also developed symptoms of post-traumatic stress disorder and depression, regardless of the type of violence, showed increased CR. The majority of studies focused on people who suffered childhood sexual abuse and half of the articles supported the hypothesis that CR is more pronounced in men than in women. Conclusions The results of this review suggest that cortisol hyperreactivity can be considered a biomarker for treatment and intervention in people with post-traumatic stress disorder and depression who suffered violence at an early age. The results also support evidence that experiencing violence alters stress response and mental health in the long term. However, it is necessary to conduct more studies, in particular studies on hyporeactivity and gender differences.

RESUMO Objetivo Analisar os resultados da reatividade do cortisol segundo um modelo de estresse experimental em adultos com ou sem transtorno psiquiátrico que foram precocemente expostos à violência durante o desenvolvimento (infância e início da adolescência) e propor um instrumento clínico para determinar indicadores biológicos de estresse. Métodos Uma revisão sistemática foi conduzida em diferentes bases de dados conforme os critérios PRISMA. Dos 231 artigos selecionados, 16 satisfizeram os critérios de inclusão. Foi realizada uma análise qualitativa dos resultados. Resultados Apesar de serem heterogêneos, os resultados indicam que adultos com exposição precoce à violência apresentam baixa reatividade do cortisol. De maneira oposta, os indivíduos que desenvolveram sintomas de transtorno de estresse pós-traumático e depressão, independentemente do tipo de violência sofrida, apresentaram elevada reatividade do cortisol. A maioria dos estudos se centrou em vítimas de abuso sexual na infância e, em metade dos artigos, sustentou-se a hipótese de que a reatividade do cortisol é mais acentuada no sexo masculino que no feminino. Conclusões Os resultados deste estudo de revisão apontam que se pode considerar a hiper-reatividade do cortisol como biomarcador para o tratamento e a intervenção de pacientes que foram expostos precocemente à violência e que apresentam transtorno de estresse pós-traumático e depressão. Além disso, é reforçada a evidência de que sofrer violência afeta a resposta ao estresse e a saúde mental a longo prazo. Porém, fazem-se necessários mais estudos, sobretudo investigando hiporreatividade e diferenças de gênero.

The role of memory in posttraumatic stress disorder: implications for clinical practice / O papel da memória no transtorno de estresse pós-traumático: implicações para a prática clínica

Abstract Introduction: Posttraumatic stress disorder (PTSD) is a highly prevalent disorder with important social consequences. Several models have been developed with the aim of understanding the mechanisms underlying its symptoms. Intrusions are idiosyncratic symptoms that commonly take the form of involuntary recollection of images or flashbacks about the traumatic event. Objective: To review how memory is conceptualized in each of these models and the implications for clinical practice. Methods: A narrative review of the literature was conducted through analysis of the perspectives of memory in theoretical models of PTSD. Results: Two main perspectives were identified: 1) models in which specific mechanisms of memory for processing traumatic events are proposed, especially those based on clinical studies, and 2) models in which common mnemonic mechanisms are utilized to explain the phenomenon, primarily based on basic experimental research studies investigating memory. The different theories based on these approaches have led to distinct psychotherapy interventions. Conclusion: In order to clarify these discrepancies, future research should aim for the methodological rigor of experimental studies, while maintaining the ecological applicability of findings. Cognitive experimental psychopathology is therefore an area on which research funding should be focused. Such studies could elucidate the role of mnemonic aspects in PTSD and how they impact psychological treatments.

Resumo Introdução: O transtorno de estresse pós-traumático (TEPT) é altamente prevalente e traz consequências sociais importantes. Diversos modelos foram desenvolvidos com o objetivo de compreender os mecanismos subjacentes aos seus sintomas. Intrusões constituem sintomas idiossincráticos, que regularmente tomam a forma de lembranças involuntárias de imagens ou flashbacks do evento traumático. Objetivo: Revisar como a memória é definida conceitualmente nos modelos teóricos propostos e as implicações para a prática clínica. Métodos: Uma revisão narrativa da literatura foi conduzida através da análise das perspectivas de memória em modelos teóricos de TEPT. Resultados: Duas perspectivas principais foram identificadas: 1) modelos com a proposição de mecanismos de memória específicos ao processamento de eventos traumáticos, especialmente apoiados em estudos clínicos, e 2) modelos em que mecanismos mnemônicos comuns são utilizados para explicar o fenômeno, primariamente baseados em estudos experimentais de base investigando memória. As diferentes teorias baseadas nessas perspectivas levaram a distintas abordagens psicoterapêuticas. Conclusões: Para clarificar essas discrepâncias, sugere-se que pesquisas futuras busquem maior rigor metodológico de estudos experimentais, mantendo a aplicabilidade ecológica dos achados. A psicopatologia cognitiva experimental é uma área na qual devem ser focados os financiamentos de pesquisa. Tais estudos podem elucidar o papel de aspectos mnemônicos no TEPT e como impactam tratamentos psicológicos.

Trauma psicológico en la atención primaria: orientaciones de manejo / Management of psychological trauma in primary care

Exposure to traumatic events is frequent in the general population and psychiatric sequelae such as post-traumatic stress disorders are common. The symptoms of psychiatric sequelae after trauma are vague, with multiple psychological and physical symptoms, which can confuse the health care professional. This paper seeks to facilitate the work in primary care, providing practical information about the diagnosis, initial management and referral of patients who have suffered traumatic experiences. Some early interventions and treatments are suggested.

Efficacy of eye movement desensitization and reprocessing beyond complex post traumatic stress disorder: a case study of EMDR in Pakistan

To demonstrate the efficacy of EMDR in complex multiple psychological trauma after failed drug treatment from selective serotonin reuptake inhibitor [SSRI] in a diagnosed case of post-traumatic stress disorder [PTSD]. Single participant of this case study, a sitting session judge of judicial governmental scaffold reported to this mental health tertiary care facility at his own accord with features of intense anxiety, depression, maladjustment issues and post- traumatic stress for a duration of several months. As a partial responder to full trial of SSRI he was enrolled for EMDR therapy to address his symptoms of intense anxiety, panic attacks, being overwhelmingly fearful, depressed, low self-esteem, inappropriate feelings of guilt, flashbacks, avoidance, nightmares, hyper-arousal and inability to perform as a judicial head in active war stricken area of northern Pakistan. Complete psychiatric evaluation was carried out and after the discontinuation of SSRIs he was scored on Impact of Event Scale [IES]. He fulfilled the diagnostic criteria for PTSD as evaluated by the English version of the PTSD module of the Structured Clinical Interview for DSM-IV administered once before commencement of EMDR. Safe place of the client was established and 8 staged protocol of EMDR was started with him. Multiple EMDR sessions were conducted. The case presented in this paper had multiple psychological trauma forms and failed drug treatment and yet it was observed that EMDR provided marked improvement in all the domains of his deficits and this was at a prompt speed as compared to cognitive behavioural therapy [CBT] which usually takes longer duration of therapy to achieve similar results. EMDR provides marked improvement in all domains of complex mental trauma and traumatic memories. Improvement attained was prompt and enduring as compared to other forms of established therapies and drug treatment indicating permanent changes happening at neurobiological levels of brain

Intervención de salud mental en niños expuestos a desastre natural / Mental health intervention in children exposed to natural disasters

Introduction: this study is part of the mental health intervention, conducted by a child psychiatry team for children exposed to the february 2010 earthquake/tsunami in a community of the VII Region that was strongly affected by the natural disaster. Objective: to describe the intervention and evaluate the effectiveness of the strategies implemented for both children and teachers. Methodology: interventions are described and classified in three categories. (1) Case report and child care consulting, referred by their teacher. (2) Psychoeducational workshops for teachers of the intervened school. (3) Self-Care day aimed at professionals of the same school. The evaluation is done through an anonymous survey designed to measure the effectiveness of the intervention. Results: 33 children were evaluated and treated, the most common diagnoses were adaptive disorders (8/33) and ADHD (11/33), and only 3 patients met the criteria for post-traumatic stress disorder (PTSD). Intervention implementation included psychoeducation for parents (100 percent), coordination with schools and local health network (100 percent), counseling (70 percent) and drug prescription (45 percent). Only 45 percent of the cases evaluated had symptoms triggered or exacerbated by the earthquake/tsunami. Regarding teacher evaluation (N: 11), 100 percent described the intervention as "very good". 90 percent considered it appropriate to the needs at the moment and as a contribution to their educational work. Conclusions: after events of this nature, many interventions take place to support the affected population. It is important to have more scientific information about the effectiveness of such interventions to prevent the development of post-traumatic psychopathology.

Introducción: este trabajo forma parte de la intervención de salud mental, realizada por un equipo de psiquiatría infantil para niños expuestos al terremoto/maremoto de febrero de 2010, en una comunidad de la VII Región fuertemente afectada por el desastre natural. Objetivos: describir la intervención realizada y evaluar la efectividad de las estrategias implementadas tanto a niños como a profesores. Metodología: se describe las intervenciones realizadas, clasificadas en 3 categorías: 1) Consultoria de casos clínicos y atención de niños derivados por sus profesores. 2) Talleres psicoeducativos a profesores de la escuela intervenida. 3) Jornada de autocuidado, dirigida a los profesionales de la misma escuela. La evaluación se realiza a través de encuesta anónima a los profesores diseñada para cuantificar la efectividad de la intervención. Resultados: se evaluaron y trataron 33 niños, los diagnósticos más frecuentes fueron Trastornos adaptativos (8/33) y Déficit atencional (11/33); sólo 3 casos cumplían criterios de Trastorno por Estrés Postraumático(TEPT). Las intervenciones utilizadas incluyeron psicoeducación a padres (100 por ciento), coordinación con colegios y red de salud municipal (100 por ciento), apoyo psicológico (70 por ciento) y farmacológico (45 por ciento). Sólo en el 45 por ciento de los casos evaluados la sintomatología se había desencadenado o agravado con el terremoto/maremoto. En relación a la evaluación de profesores (n: 11), 100 por ciento consideró la intervención como "muy buena". Un 90 por ciento la consideró adecuada a las necesidades y constituyó un aporte a su quehacer educativo. Conclusiones: tras eventos como éste, se realizan variadas intervenciones de apoyo a la población afectada. Es importante contar con mayor información científica acerca de la efectividad de dichas intervenciones para prevenir el desarrollo de psicopatología postraumática.

Intervención grupal en víctimas de represión política con trastorno de estrés postraumático crónico a través de técnicas de arteterapia / Group intervention in victims of political repression with chronic posttraumatic stress disorder through art therapy techniques

Este artículo pretende dar a conocer una experiencia grupal mediante técnicas de Arteterapia en pacientes con diagnóstico de Estrés Postraumático Crónico, usuarios del Programa PRAIS Coquimbo, víctimas de represión política. Para ello mostraremos la importancia del arte en el desempeño de intervenciones en salud mental, especialmente en trastornos complejos en los que la verbalización y canalización de emociones es poco factible. Se describirá el proceso a través del cual se logra no sólo un trabajo individual que fortalece destrezas artísticas, sino también cómo el acompañamiento mutuo y empatía permiten la resignificación del trauma, en un ambiente de horizontalidad y respeto por las vivencias de los otros. Finalmente, se detallarán los resultados del trabajo realizado, en que los participantes manifiestan su satisfacción frente al entorno.

This article seeks to highlight a group experience through techniques of art therapy in patients with a diagnosis of chronic Post-traumatic Stress, in the PRAIS Program users in Coquimbo, victims of political repression. We will show the importance of art in the performance of mental health interventions, especially in complex disorders in which the verbalization and channeling of emotions becomes unfeasible. We describe the process by which it is achieved not only an individual work which strengthens artistic skills, but also how the mutual support and empathy enable the redefinition of trauma, in an atmosphere of horizontality and respect for the experiences of others. Finally we detail the results of work performed, in which participants expressed their satisfaction with the environment.

Transtornos de ansiedade: terapia com estimulação magnética transcraniana / Anxiety disorders: treatment with transcranial magnetic stimulation

Dentre os transtornos psiquiátricos, os transtornos de ansiedade (TAs) são os mais comuns, com prevalência em torno de 20% na população e, portanto, provocam grande prejuízo a pacientes e familiares. São vários os subtipos de transtornos de ansiedade e um diagnóstico correto se baseia em uma avaliação clínica cuidadosa. No presente artigo apresentamos os diagnósticos e os achados mais recentes sobre o tratamento com estimulação magnética transcraniana repetitiva (EMTr) para o transtorno de pânico, transtorno obsessivo-compulsivo, transtorno de estresse pós-traumático e fobia social.

Among psychiatric disorders, anxiety disorders (ATs) are the most common, with a prevalence of around 20% in the population and with great harm to patients and families. There are several subtypes of anxiety disorders and a correct diagnosis is based on a careful clinical assessment. In this paper we present the findings and the latest findings about treatment with repetitive transcranial magnetic stimulation (rTMS) for panic disorder, obsessive-compulsive disorder, post-traumatic stress and social phobia.

Effects of Cognitive Behavioral Therapy Program on Mental Health Problems in Children Dealing with Trauma: Focused on Community District Victimized by Oil Spill

PURPOSE: This study was done to evaluate the effects of cognitive behavioral therapy in a victimized community district and to determine if the program is an effective nursing intervention to reduce posttraumatic stress disorder symptom, depression and state anxiety. METHODS: A nonequivalent control group design was used for the study. The participants, 32 elementary school students, were selected from grades 4, 5, 6 and each student was assigned to either the experimental (16) or control (16) group. Cognitive behavioral therapy was used as the experimental treatment from April 9 to May 28, 2009. The experimental group received cognitive behavior therapy intervention 8 times. Data analysis was done using ANCOVA with SPSS 17.0. RESULTS: After the intervention, the experimental group showed significantly lower levels of posttraumatic stress disorder symptoms than the control group. CONCLUSION: The findings from this study suggest that cognitive behavioral therapy is an effective nursing intervention to decrease the level of mental health problems of children in victimized district. Further research is required in order to identify the continuous effects of cognitive behavioral therapy.

Prazosina de liberação lenta para pacientes com transtorno do estresse pós-traumático resistentes aos ISRS / Slow-release prazosin for SSRI-resistant posttraumatic stress disorder patients

CONTEXTO: Prazosina, um antagonista de receptores alfa-1 adrenérgicos, é utilizada no tratamento de pesadelos e insônia relacionados com TEPT. Apesar das evidências sugerindo sua eficácia também no tratamento de sintomas gerais de TEPT, sua curta meia-vida (2-3 horas) pode limitar seus efeitos terapêuticos.OBJETIVO: Descrever quatro casos de pacientes com TEPT resistentes aos inibidores de recaptação de serotonina ou de serotonina e adrenalina (terapia convencional) tratados com uma apresentação de prazosina de liberação lenta.MÉTODOS: Quatro pacientes com TEPT grave, resistentes à terapia convencional, tiveram a prazosina de liberação lenta (meia-vida de 10,8 horas) adicionada as suas prescrições por pelo menos três meses. Os sintomas de TEPT foram avaliados pela PCL-C e pelos itens referentes a pesadelos e insônia da CAPS, na linha de base e no final do período de observação de cada paciente.RESULTADOS: Dois pacientes mostraram melhora dos sintomas gerais de TEPT (redução de 35,7% e 11,9% nos escores da PCL-C), e três mostraram melhora de pesadelos e insônia (nos escores da CAPS). O único paciente que recebeu doses da prazosina pela manhã e ao deitar-se foi o que mostrou a maior melhora dos sintomas gerais de TEPT.CONCLUSÃO: Possivelmente, a sustentação do bloqueio da atividade noradrenérgica no sistema nervoso central promovida pela prazosina de liberação lenta durante o dia se faz necessária para a melhora de sintomas residuais de TEPT em pacientes em tratamento convencional com antidepressivos.

BACKGROUND: Prazosin is an antagonist of alpha-1 adrenergic receptor used to treat PTSD-related nightmares and insomnia. Although evidence suggests that it is also effective in the treatment of general symptoms of PTSD, its short half-life (2-3 hours) may limit its therapeutic effects.OBJECTIVE: To describe four cases of patients with PTSD resistant to selective serotonin reuptake inhibitors (SSRIs) or selective serotonin/noradrenaline reuptake inhibitor (SNRIs) therapy (conventional therapy) treated with slow-release prazosin presentation.METHODS: Four patients with severe PTSD resistant to conventional therapy received slow-release prazosin (half-life of 10.8 hours) added to their prescription for at least three months. PTSD symptoms were evaluated by the PCL-C, together with nightmares and insomnia items of CAPS, at baseline and at the last observation of each patient.RESULTS: Two patients showed improvement in general symptoms of PTSD (reduction of 35.7% and 11.9% in PCL-C scores), and three showed relief from nightmares and insomnia (CAPS scores). The only patient who received morning and bedtime doses of prazosin showed the greatest improvement in general symptoms of PTSD.DISCUSSION: It is possible that the sustained blockade of noradrenergic activity in the central nervous system provided by slow-release prazosin during the day is necessary to further ameliorate residual PTSD symptoms in patients receiving conventional antidepressant therapy.